Anti-fungal Testing

Special Precautions/Comments:

N.B.: Timing of samples based on required anti-fungal investigation:

  • Fluconazole – Pre dose sample and a post dose sample taken 2 hours after oral administration
  • Itraconazole – Pre dose sample only, taken up to an hour before dosing
  • Posaconazole – Pre dose sample taken immediately before administration
  • Voriconazole – Pre dose sample taken immediately before administration

Interferences: It is best to avoid use of blood tubes containing gel. Gel may bind the analyte which may result in an artificially lower result being obtained, interpreted and reported.

Method: Anti-fungal specific assay for the detection of anti-fungal levels and their active metabolite. Calibration: – EQA scheme: – IQC: –

Interpretation: Results will be given in mg/L. Specific reference ranges will be provided upon reporting.

For further information contact Mycology Reference Laboratory Bristol .

Additional Information:

Background information: When patients are being treated with anti-fungals, it is important that levels are monitored to ensure that they are not so high that they are toxic or so low that they are ineffectual.