Soluble Transferrin Receptor (STFR)

Code:
STFR

Sample Type:

Serum (Gold Top)

Minimum volume: 1 mL

Ref Ranges/Units:

1.71 – 4.13 mg/L 

Turnaround:

Same Day

Stability:

6 days at 15‑25°C 
15 days at 2‑8°C 
13 weeks at -20°C 
Freeze only once 

Special Precautions/Comments:

Additional Information:

Cellular uptake of iron is controlled by expression of the transferrin receptor on cell membranes. In plasma, soluble transferrin receptor (STFR) forms a complex with transferrin. Levels of STFR are directly proportional to membrane-bound transferrin receptors.  

SFTR is measured alongside ferritin in the investigation of iron deficiency and a STFR-ferritin ratio is calculated: 

  • <1 iron deficiency unlikely 
  • >2 iron deficiency likely 
  • Ratio 1-2 AND raised SFTR – check haemoglobin possibly a short course of iron 
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